What a substance is capable of causing under some conditions.
Chemical & Exposure Guide
Hazard is not the same as exposure.
These profiles explain what documented contaminants can do, how exposure may occur, what is known about long-term effects, and where uncertainty remains. A chemical named at a site does not establish that a person, community, or wildlife population was exposed or harmed.
Where and when a laboratory measured a substance.
Contact through air, water, food, soil, skin, or work.
Depends on dose, route, frequency, duration, and susceptibility.
Starting collection
20 priority profiles
20 of 20 profiles
Per- and polyfluoroalkyl substances
PFAS
Also known as PFOA, C8, APFO, PFOS, PFNA, PFDA, PFHxS, PFBS, AFFF
PFAS are a large family of manufactured chemicals used in firefighting foams, fluoropolymer production, coatings, plating, textiles, paper, and many other applications.
Read exposure and effects profile →Volatile organic compound
Benzene
Benzene is a volatile component of gasoline and petroleum and was also used in coke production, chemical manufacturing, solvents, and industrial processes.
Read exposure and effects profile →Chlorinated solvent
Trichloroethylene
Also known as TCE
TCE was widely used to degrease metal parts and in other industrial cleaning and manufacturing operations.
Read exposure and effects profile →Chlorinated solvent
Tetrachloroethylene
Also known as PCE, PERC, Perchloroethylene
PCE has been used extensively in dry cleaning, textile processing, metal degreasing, and industrial cleaning.
Read exposure and effects profile →Volatile chlorinated compound
Vinyl chloride
Vinyl chloride is used to manufacture PVC and can also form underground when TCE, PCE, and related solvents break down.
Read exposure and effects profile →Persistent chlorinated compounds
PCBs
Also known as Polychlorinated biphenyls
PCBs were used in electrical equipment, hydraulic systems, heat-transfer fluids, building materials, and industrial processes before most U.S. uses were banned.
Read exposure and effects profile →Combustion and coal-tar compounds
PAHs
Also known as Polycyclic aromatic hydrocarbons
PAHs form during incomplete combustion and occur in coal tar, coke-oven waste, creosote, petroleum, soot, and contaminated sediment.
Read exposure and effects profile →Persistent chlorinated byproducts
Dioxins
Also known as Chlorinated dioxins, CDDs
Dioxins can form as unwanted byproducts of combustion and certain chlorine-based industrial processes.
Read exposure and effects profile →Toxic metal
Lead
Lead has been used in paint, batteries, metalworking, fuels, plumbing, pigments, ammunition, and many industrial products.
Read exposure and effects profile →Metalloid
Arsenic
Arsenic occurs naturally and has also been used in pesticides, wood treatment, metal production, pigments, and industrial processes.
Read exposure and effects profile →Toxic metal
Mercury
Also known as Methylmercury
Mercury has been used in industrial equipment and chemical production and can also enter the environment through combustion and atmospheric deposition.
Read exposure and effects profile →Toxic metal
Cadmium
Cadmium has been used in batteries, pigments, plating, alloys, plastics, and metal production.
Read exposure and effects profile →Metal with multiple chemical forms
Chromium
Also known as Hexavalent chromium, Chromium VI
Chromium compounds are used in plating, pigments, leather tanning, corrosion control, alloys, and refractory materials.
Read exposure and effects profile →Reactive chemical group
Cyanide
Cyanide compounds have been used in metal finishing, electroplating, coke production, mining, and chemical manufacturing.
Read exposure and effects profile →Volatile sulfur compound
Carbon disulfide
Also known as CS2
Carbon disulfide has been used to manufacture rayon, cellophane, rubber chemicals, and sponge or cellulose products.
Read exposure and effects profile →Emerging solvent contaminant
1,4-Dioxane
1,4-Dioxane has been used as a solvent stabilizer and in manufacturing and may occur with chlorinated-solvent contamination.
Read exposure and effects profile →Organochlorine pesticide
DDT
Also known as DDD, DDE
DDT was widely used as an insecticide. DDE and DDD are persistent breakdown products commonly included in environmental investigations.
Read exposure and effects profile →Fibrous mineral hazard
Asbestos
Asbestos was used in insulation, fireproofing, cement, roofing, flooring, brakes, gaskets, and many industrial buildings and products.
Read exposure and effects profile →Radioactive metal
Uranium
Also known as Depleted uranium
Uranium occurs naturally and has been mined, refined, processed, and used in nuclear fuel and military or industrial applications.
Read exposure and effects profile →Radioactive alkaline-earth metal
Radium
Also known as Ra-226, Ra-228
Radium occurs naturally in uranium and thorium decay chains and has historical industrial, medical, and luminous-paint uses.
Read exposure and effects profile →